カルプロニウム塩化物外用液5%
CH
Carpronium hair lotion (Karoyan, Frojin)
Carpronium chloride (topical)
Carpronium is a Japan-only hair growth ingredient that has been sold as Karoyan since 1973. It increases scalp blood flow and is milder than minoxidil, with no equivalent abroad. For male pattern hair loss, minoxidil, finasteride and dutasteride have far stronger evidence.
At a glance
- Prescription status
- Prescription and OTC
- Over the counter
- Class 3
- Bringing it into Japan
- ✓ 1 month Rx / 2 months OTC
- Names abroad
- 卡普氯铵
Over the counter
Karoyan products (1–2% carpronium) are OTC Class 3; the 5% prescription lotion Frojin is used by dermatologists for alopecia areata.
Finding it in a Japanese drugstore
- Look for this on the package
- カルプロニウム（カロヤン・フロジン）
- Carpronium chloride (topical)
- Common product names
- カロヤンプログレEXカロヤンガッシュ
- Category printed on the package
- Class 3
- Sold at any drugstore or pharmacy, and online.
Show this page to the pharmacist or staff. Prices and packaging vary by store, so look for the Japanese ingredient name.
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Prescription products in Japan
2 productsProducts on Japan's national drug price list. Prescription only: a clinic visit is needed, and pharmacies may substitute a generic with the same ingredient.
| Generic | 2 generic products |
|---|---|
| Dosage forms | Topical |
Product names are shown in Japanese, exactly as printed on the package and the prescription. Show this page at the pharmacy.
All listed products (2) · Drug price list as of 2026-08-12
| カルプロニウム塩化物外用液5%「CH」 · Generic | Topical · ¥7.4/mL |
|---|---|
| フロジン外用液5% · Generic | Topical · ¥15.4/mL |
Bringing it into Japan
Up to a 1-month supply of prescription medicine, or 2 months of OTC medicine, without any paperwork. For more, apply for a Yakkan Shoumei (import confirmation) before travel.
Getting it prescribed in Japan
Any clinic can prescribe it after a consultation. Bring the original packaging or a medication list. Use the hospital finder to find clinics with English-speaking staff or an international patient office.
Names abroad
| China | 卡普氯铵 |
|---|
Sources
- Health Insurance Claims Review & Reimbursement Services — Drug master (NHI drug price list) shinryohoshu.mhlw.go.jp — 2026-08-12
- Ministry of Health, Labour and Welfare — Bringing medicines for personal use into Japan mhlw.go.jp
This page describes how a medicine is regulated and sold in Japan. It is not medical advice and does not cover dosing for your situation; follow your doctor's and pharmacist's instructions.