Regenerative cosmetic treatment (unregulated)

Exosome therapy (stem-cell supernatant)

Exosome / stem-cell culture supernatant

Exosome and stem-cell supernatant treatments are marketed aggressively by Japanese anti-aging clinics, often to visitors from China, with claims about skin, hair and longevity. None is approved, quality control is up to each clinic, and Japan's regenerative medicine law does not cover these cell-free products. Approach with the same caution as any unproven therapy.

At a glance
Prescription status
Not approved in Japan
Over the counter
Not sold OTC
Bringing it into Japan
✓ 1 month Rx / 2 months OTC
Names abroad
Exosome therapy (unapproved) · 엑소좀

Over the counter

No exosome product is approved in Japan. Clinics offer drips and injections under the 'doctor's discretion' rule, self-paid at ¥30,000–150,000; the health ministry has warned about unproven claims.

Prescription products in Japan

0 products

Products on Japan's national drug price list. Prescription only: a clinic visit is needed, and pharmacies may substitute a generic with the same ingredient.

Dosage forms

Product names are shown in Japanese, exactly as printed on the package and the prescription. Show this page at the pharmacy.

All listed products (0) · Drug price list as of 2026-08-12

Bringing it into Japan

Not approved in Japan, so it cannot be prescribed or bought here. Bringing your own supply for personal use follows the normal rule: up to 1 month of prescription medicine without paperwork.

How to apply for a Yakkan Shoumei (article)

Names abroad

USExosome therapy (unapproved)
Korea엑소좀
China外泌体
Taiwan外泌體

Sources

  1. Health Insurance Claims Review & Reimbursement Services — Drug master (NHI drug price list) shinryohoshu.mhlw.go.jp — 2026-08-12
  2. Ministry of Health, Labour and Welfare — Bringing medicines for personal use into Japan mhlw.go.jp

This page describes how a medicine is regulated and sold in Japan. It is not medical advice and does not cover dosing for your situation; follow your doctor's and pharmacist's instructions.