Antiepileptic

Topiramate (Topamax)

Topiramate · トピナ

Topiramate (Topina, 25, 50 and 100 mg) is approved in Japan only as an add-on for epilepsy. Patients taking it abroad for migraine or as part of Qsymia will find Japanese doctors reluctant to prescribe it for those uses; bring your own supply under the 1-month rule.

At a glance
Prescription status
Prescription only
Over the counter
Not sold OTC
Bringing it into Japan
✓ 1 month Rx / 2 months OTC
Names abroad
Topamax

Over the counter

Prescription only. Approved in Japan for epilepsy only; migraine prevention and weight loss are off-label here.

Prescription products in Japan

7 products

Products on Japan's national drug price list. Prescription only: a clinic visit is needed, and pharmacies may substitute a generic with the same ingredient.

Brand namesトピナ
Generic3 generic products
Dosage formsOral
Strengths (oral)25mg · 50mg · 100mg
Official price (per tablet or unit)¥8.6 – ¥92.8
Official NHI drug price. Patients with Japanese insurance pay 10–30%; visitors without it pay the full price plus consultation fees.

Product names are shown in Japanese, exactly as printed on the package and the prescription. Show this page at the pharmacy.

All listed products (7) · Drug price list as of 2026-08-12
トピナ細粒10%Oral · ¥92.8/g
トピナ錠100mgOral · ¥59.9/tablet
トピナ錠25mgOral · ¥16.5/tablet
トピナ錠50mgOral · ¥36.1/tablet
トピラマート錠100mg「アメル」 · GenericOral · ¥25.6/tablet
トピラマート錠25mg「アメル」 · GenericOral · ¥8.6/tablet
トピラマート錠50mg「アメル」 · GenericOral · ¥18.4/tablet

Bringing it into Japan

Up to a 1-month supply of prescription medicine, or 2 months of OTC medicine, without any paperwork. For more, apply for a Yakkan Shoumei (import confirmation) before travel.

How to apply for a Yakkan Shoumei (article)

Getting it prescribed in Japan

Any clinic can prescribe it after a consultation. Bring the original packaging or a medication list. Use the hospital finder to find clinics with English-speaking staff or an international patient office.

Find a clinic by language

Names abroad

USTopamax, Qsymia (combination)
UKTopamax
Korea토파맥스
China妥泰
Taiwan妥泰

Sources

  1. Health Insurance Claims Review & Reimbursement Services — Drug master (NHI drug price list) shinryohoshu.mhlw.go.jp — 2026-08-12
  2. Ministry of Health, Labour and Welfare — Bringing medicines for personal use into Japan mhlw.go.jp

This page describes how a medicine is regulated and sold in Japan. It is not medical advice and does not cover dosing for your situation; follow your doctor's and pharmacist's instructions.