Type 2 diabetes medicine (biguanide)

Metformin

Metformin hydrochloride · メトグルコ · グリコラン

Metformin is the standard first-line medicine for type 2 diabetes. Japanese brands are Metgluco and Glycoran, with many generics in 250 mg and 500 mg tablets. Extended-release metformin (Glucophage XR) is not approved in Japan, so visitors on XR may be switched to the immediate-release tablet.

At a glance
Prescription status
Prescription only
Over the counter
Not sold OTC
Bringing it into Japan
✓ 1 month Rx / 2 months OTC
Names abroad
Glucophage

Over the counter

Prescription only.

Prescription products in Japan

26 products

Products on Japan's national drug price list. Prescription only: a clinic visit is needed, and pharmacies may substitute a generic with the same ingredient.

Brand namesメトグルコ · グリコラン
Generic23 generic products
Dosage formsOral
Strengths (oral)250mg · 500mg
Official price (per tablet or unit)¥10.5 – ¥10.8
Official NHI drug price. Patients with Japanese insurance pay 10–30%; visitors without it pay the full price plus consultation fees.

Product names are shown in Japanese, exactly as printed on the package and the prescription. Show this page at the pharmacy.

All listed products (26) · Drug price list as of 2026-08-12
グリコラン錠250mgOral · ¥10.5/tablet
メトグルコ錠250mgOral · ¥10.8/tablet
メトグルコ錠500mgOral · ¥10.8/tablet
メトホルミン塩酸塩250mgMT錠 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩500mgMT錠 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠250mgMT「DSEP」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠250mgMT「DSPB」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠250mgMT「JG」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠250mgMT「TCK」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠250mgMT「TE」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠250mgMT「トーワ」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠250mgMT「ニプロ」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠250mgMT「三和」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠250mgMT「日医工」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠250mgMT「明治」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠250mg「SN」 · GenericOral · ¥10.5/tablet
メトホルミン塩酸塩錠500mgMT「DSEP」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠500mgMT「DSPB」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠500mgMT「JG」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠500mgMT「TCK」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠500mgMT「TE」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠500mgMT「トーワ」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠500mgMT「ニプロ」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠500mgMT「三和」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠500mgMT「日医工」 · GenericOral · ¥10.8/tablet
メトホルミン塩酸塩錠500mgMT「明治」 · GenericOral · ¥10.8/tablet

Bringing it into Japan

Up to a 1-month supply of prescription medicine, or 2 months of OTC medicine, without any paperwork. For more, apply for a Yakkan Shoumei (import confirmation) before travel.

How to apply for a Yakkan Shoumei (article)

Getting it prescribed in Japan

Any clinic can prescribe it after a consultation. Bring the original packaging or a medication list. Use the hospital finder to find clinics with English-speaking staff or an international patient office.

Find a clinic by language

Names abroad

USGlucophage, Fortamet
UKGlucophage
Korea글루코파지, 다이아벡스
China格华止
Taiwan庫魯化

Frequently asked questions (FAQ)

How much metformin can I bring for a long stay?

Up to 1 month without paperwork. For more, apply online for a Yakkan Shoumei (import confirmation) before travel, or plan to get a prescription from a Japanese doctor.

Sources

  1. Health Insurance Claims Review & Reimbursement Services — Drug master (NHI drug price list) shinryohoshu.mhlw.go.jp — 2026-08-12
  2. Ministry of Health, Labour and Welfare — Bringing medicines for personal use into Japan mhlw.go.jp

This page describes how a medicine is regulated and sold in Japan. It is not medical advice and does not cover dosing for your situation; follow your doctor's and pharmacist's instructions.